A gastric cytoprotectant is any medication that combats ulcers not by reducing gastric acid but by increasing mucosal protection. Examples of gastric cytoprotective agents include prostaglandins which protect the stomach mucosa against injury by increasing gastric mucus secretion. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins and thereby make the stomach more susceptible to injury. Gastric cytoprotective drugs include carbenoxolone, … WebNov 16, 2006 · The cytoprotective protein C pathway for APC anti-inflammatory activity. Anti-inflammatory effects of APC include APC's effects on vascular endothelial cells and APC's effects on leukocytes. Inhibition of inflammatory gene expression on endothelial cells by APC is EPCR and PAR-1 dependent (green arrow). APC also down-regulates …
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WebSome of the drugs widely used in therapy of peptic ulcer are cytoprotective e.g. sucralfate, colloidal bismuth and aluminium containing antacids. As the concept of gastric cytoprotection is becoming widely accepted, the list of drugs which have shown a cytoprotective action in animal experiments is growing rapidly. This list includes zinc ... WebSince the first demonstration of cytoprotection by prostaglandins many other agents have been claimed to be cytoprotective. Essential fatty acids: arachidonic and linoleic, licorice products, sucralfate, antacids and sulfhydryl compounds all possess cytoprotective properties. All of these compounds are able to prevent or reduce gastric mucosal ... ophthalmologist in mullica hill nj
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WebJan 4, 2024 · Autophagy, a process of cellular self-degradation and cell survival whereby the cell generates energy and metabolic intermediates under conditions of stress (i.e., nutrient deprivation), is also commonly induced in tumor cells in response to chemotherapy and radiation. While chemotherapy-induced autophagy and radiation-induced autophagy are … WebJan 25, 2024 · Cytoprotective therapies for AIS have remained elusive — a long history of failures and disappointments spans more than 40 years. Many pharmaceuticals that target different components of the ischaemic cascade have produced promising results in animal models of stroke with varying degrees of methodological rigour, but none has had clear ... WebThis research aims to study the antioxidant and cytoprotective effect of protein hydrolysate produced from blue-green algae, Arthrospira platensis (APH). ... ophthalmologist in murrells inlet sc