Cisplatin or carboplatin
WebDec 7, 2024 · In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. Methods A total of 1305 patients with previously untreated ES-SCLC were included in this study. Data from five … WebOct 20, 2024 · Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years’ follow-up. …
Cisplatin or carboplatin
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WebMar 30, 2024 · FDA approves durvalumab for extensive-stage small cell lung cancer On March 27, 2024, the Food and Drug Administration approved durvalumab (IMFINZI, AstraZeneca) in combination with etoposide and... WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose …
WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks. WebDec 4, 2024 · Comparison of cisplatin and carboplatin exposure on germ cell populations of the human foetal testis. Quantification of germ cell subpopulations in the human foetal testis 72 h (a–c) and 240 h (d–f) following exposure to vehicle (VEH), cisplatin (CIS; 0.5 …
WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … WebChemoradiotherapy with paclitaxel liposome plus cisplatin for locally advanced esophageal squamous cell carcinoma: A retrospective analysis ... (TF), and paclitaxel and carboplatin (TC) schemes, which did not show significant survival benefits. 7 , 10 , 12 Currently, paclitaxel‐based chemotherapy is a concurrent regimen commonly used in clinics.
WebCarboplatin / pharmacology Cisplatin / metabolism Cisplatin / pharmacology* Cisplatin / therapeutic use DNA / drug effects Drug Resistance / genetics Gene Expression Regulation, Neoplastic / drug effects ...
WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … thunderbolt smartcard readerWebJul 1, 2000 · Carboplatin provides an improved therapeutic index compared to cisplatin, especially in terms of reduced nonhematologic toxicities. However, added hematologic toxicity may be problematic when combining carboplatin with other myelosuppressive chemotherapeutic agents. thunderbolt software co toWebApr 10, 2024 · Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, … thunderbolt software dell xpsWebSep 12, 2024 · While physicians may use cisplatin and carboplatin for lung or ovarian cancer, cisplatin is also used to treat bladder and testicular cancer. The ordinary dosage of carboplatin is up to three times higher than that of cisplatin in many cases, but the … thunderbolt software download intelWebJul 19, 2016 · Carboplatin yielded comparable results to cisplatin in concurrent chemo-radiation for locally advanced cervical cancer. In addition, carboplatin was associated with a better compliance rate and was associated with less of anemia, neutropenia and nephrotoxicity. Peer Review reports Backgrounds thunderbolt software download dell tb16WebMay 10, 2012 · Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data. Our meta-analysis of individual patient data suggests no differences in efficacy between cisplatin … thunderbolt software download lenovoWebBoth chemo drugs are hard on the bone marrow & kidneys--they both cause neuropathy & can cause hearing loss. The carboplatin is a little more gentle on the kidneys so you must have good kidneys. For sure, you should drink a lot of water before & after chemo … thunderbolt software download hp