Cisplatin and hypokalemia
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf Web• Cisplatin is a common cause of hypomagnesemia and hypokalemia due to renal magnesium (Mg) and potassium (K) losses. Magnesium plays an important role in the maintenance of intracellular K. An unrecognized and untreated Mg depletion can lead to a refractory K repletion.
Cisplatin and hypokalemia
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WebApr 1, 2024 · Triple disorder with metabolic alkalosis, metabolic acidosis, and respiratory alkalosis Compensated metabolic alkalosis Analyzing an acid-base disturbance is a 5-step process. Step 1: Look at the pH. Our patient’s arterial pH was 7.55, which, being higher than 7.45, shows a state of alkalemia. WebMar 25, 2024 · The most common laboratory findings include: hyponatremia, hyperkalemia, and anemia [ 4 ]. Hydrocortisone is the mainstay of treatment, and fludrocortisone is added to replace mineralocorticoid deficiency. Usually, hydrocortisone doses are divided into two or three doses, with the highest dose in the morning to mimic the circadian rhythm.
WebJul 24, 2024 · Cisplatin, a chemotherapeutic drug, can also cause hypocalcemia through hypomagnesemia. Foscarnet can cause hypocalcemia by forming complexes with ionized calcium, thereby … Webis a major concern when prescribing cisplatin. Renal dysfunction due to cisplatin may manifest as renal insufficiency, hypokalemia and hypomagnesemia. The risk for these …
Webis a major concern when prescribing cisplatin. Renal dysfunction due to cisplatin may manifest as renal insufficiency, hypokalemia and hypomagnesemia. The risk for these adverse effects is related to the dose and interval of cisplatin and may be minimized by adequate hydration. Geriatric patients may also be at increased risk. WebThere is no relationship between the presence or severity of Cisplatin side effects and effectiveness of cisplatin. The following side effects are common(occurring in greater than 30%) for patients taking Cisplatin: Nausea and vomiting. Nausea may last up …
WebHypomagnesemia generally resolves with cessation of therapy. Cisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin.
WebJun 1, 2024 · Hypomagnesemia and hypokalemia are side effects of certain chemotherapies, including cisplatin, cetuximab, eribulin, and ifosfamide. When patients concurrently receive chemotherapy and take medications that cause hypomagnesemia or hypokalemia, electrolyte imbalances are amplified. ttl 価格Web8 mg PO/IV 30 to 60 minutes pre- CISplatin, then 8 mg PO/IV every 12 hours x 6 doses aprepitant . 125 mg PO 30 to 60 minutes pre-CISplatin on day 1, then 80 mg PO daily … phoenix home builder azWebAug 1, 2004 · Nephrotoxicity after cisplatin administration usually manifests as increased serum creatinine and blood urea nitrogen (BUN) levels, as well as electrolyte … ttl信号WebApr 15, 2024 · Eventually, nephrotoxicity complicated by hypomagnesaemia was confirmed, and cisplatin-induced nephrotoxicity led to the final diagnosis of a familial form of … ttl刷机WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative … phoenixhome4rentWebDigitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects. All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as ... ttl光猫Web21 hours ago · The EARLY-MYO-BC trial is the first to explore the cardiac impacts of pyrotinib in the neoadjuvant setting for this patient population. Patients are currently … phoenix home and garden magazine